Colchester inflicted a first home defeat on Newport in seven months as they secured a 2-1 victory at Rodney Parade.
Goals from Ryan Jackson and Mikael Mandron gave the visitors the three points.
The Exiles dominated the first half, but Colchester looked dangerous on the counter-attack with Brandon Hanlan forcing an important save from Joe Day.
John McGreal's Colchester had their first chance when Mandron's header went close just after half time.
Visiting keeper Sam Walker was forced to keep Padraig Amond's...